I love Visual Studio about 90% of the time, but that last 10% it is such a PITA it makes me want to launch my monitor off the desk.

My latest annoyances:

• It won't remember my toolbar settings. I don't want any toolbars, ever. Quit popping open the CSS editor or XML editor or text editor everytime I open a file.
• Doesn't remember which regions I had expanded or collapsed and as far as I know there is no way to tell it to always open files with the regions expanded.
• When editing CSS or HTML the damn error list wants to pop up each time I start a tag and haven't finished it yet. First of all, don't pop up at all. And if you're going to ... give me a couple seconds to finish what I'm doing.

The best part ... ReSharper :)

EDIT [Jay Bazuzi]: It seems like this discussion is only productive if it's focused on the latest released version. Set the title to VS2008.