I am wondering what benefits will give me to move all website content files from the default inetpub directory (C:) to something like D:\wwwroot. By default IIS creates separate application pool for each website and I am using the built-in user and group (IURS) as the authentication method. I’ve made sure each site directory has the appropriate permission settings so I am not sure what benefits I will gain. Some of the environment settings are as below:

• VMWare Windows 2008 R2 64
• IIS 7.5
• C:\inetpub\site1
• C:\inetpub\site2

Also as this article (moving the iis7 inetpub directory to a different drive) points out, not sure if it's worth the trouble to migrate files to a different drive:

PLEASE BE AWARE OF THE FOLLOWING: WINDOWS SERVICING EVENTS (I.E. HOTFIXES AND SERVICE PACKS) WOULD STILL REPLACE FILES IN THE ORIGINAL DIRECTORIES. THE LIKELIHOOD THAT FILES IN THE INETPUB DIRECTORIES HAVE TO BE REPLACED BY SERVICING IS LOW BUT FOR THIS REASON DELETING THE ORIGINAL DIRECTORIES IS NOT POSSIBLE.