I am running SysInternal's Desktops 1.02 and FireFox 3.6.2. I have noticed that while I can have IE8 open in multiple Virtual Desktops, you can not Firefox. If you try you get the error message:

Firefox is already running, but is not responding. To open a new window, you must close the existing FireFox process, or restart your system.

I did a little digging around to work around this and came up with creating a second profile via the Firefox profile manager (accessed by starting FF with the "-p" switch). This unfortunately created a new problem which is my add-ons (of which I use many) do not stay synchronized between profiles.

Is there a better approach here?