Has anyone rolled out Google Chrome to a medium / large organisation?

I would like to suggest it to our management (because I think it would work very nicely with some of our intranet applications), and I would like to find out what problems (if any) the rest of the world has been experiencing with it.

Have you found any problems?
I'm thinking of enterprise-level problems. I'm thinking that we can solve anything that requires a specific configuration / proxy setting / etc.
I don't really know what I think might be a problem, but I wonder if there are any usability problems that occur when non-geeks use it? Or problems which only rear their ugly heads when you've got 50 users all doing something unexpected.

Any helpful information or suggestions would be appreciated. Thanks.

UPDATED: We tend to use Microsoft stuff, so Sharepoint, IIS, SQL Server, are typical building blocks of internal sites. (Thanks, @Jim, for reminding me to mention that).