I realize that in general the C and C++ standards gives compiler writers a lot of latitude. But in particular it guarantees that POD types like C struct members have to be laid out in memory the same order that they're listed in the structs definition, and most compilers provide extensions letting you fix the alignment of members. So if you had a header that defined a struct and manually specified the alignment of its members, then compiled two apps with different compilers using the header, shouldn't one app be able to write an instance of the struct into shared memory and the other app be able to read it without errors?

I am assuming though that the size of the types contained is consistent across two compilers on the same architecture (it has to be the same platform already since we're talking about shared memory). I realize that this is not always true for some types (e.g. long vs. long long in GCC and MSVC 64-bit) but nowadays there are uint16_t, uint32_t, etc. types, and float and double are specified by IEEE standards.