When X.org boots up, Synaptics touchpad works well. But when I remove the module it falls back to /dev/input/mice and don't use normal driver even when touchpad is available again.

Xorg.0.log:
...
(II) XINPUT: Adding extended input device "Synaptics Touchpad" (type: TOUCHPAD)
(--) Synaptics Touchpad: touchpad found

# { rmmod psmouse && echo mem > /sys/power/state && modprobe psmouse; }

(WW) : No Device specified, looking for one...
(II) : Setting Device option to "/dev/input/mice"
...

How to tell X.org to try it's InputDevice again (without restarting X server)?

P.S. rmmod psmouse is needed to prevent crashing of Acer Extensa 5220 when resuming from suspend-to-ram.

Update: Found answer myself: Doing xinput set-int-prop "Synaptics Touchpad" "Device Enabled" 8 1 after reloading the kernel module reloads touchpad. Now suspend-to-ram works OK.