PHP, ColdFusion, and ASP (among many others) are usually sold on their strengths. What are their weaknesses? If one were to develop a niche product to handle the things that these products weren't so good at, what should it focus on?

EDIT

I'm trying to figure out what things PHP etc are bad at. They're all good at doing the nuts and bolts stuff, if one is looking with a bottom-to-top mindset. I'm thinking a little more globally, more top-to-bottom; what's difficult to achieve in PHP/ASP/CF without thousands of lines of code and twenty minutes of server time?

EDIT

Suppose company A comes up to you and says, "We want you to do x in PHP." What values of x will cause you to say, "Forget it, buddy, no one in their right mind would use PHP for that"?

(swap PHP in the above quote for your favourite tool)

EDIT

Have we got to the point where everyone's needs can be met with PHP frameworks, Rails and ... er ... Java?