What is the best color combination for readability, easy of use, and reduced eye strain?

Posted by Nick Berardi on Stack Overflow See other posts from Stack Overflow or by Nick Berardi
Published on 2009-07-20T16:30:29Z Indexed on 2010/05/29 4:42 UTC
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I am trying to pick out the optimal set of colors for a new website project.

I want to do a traditional black on white look and feel for the main content. However my partner on the project wants to do a color combination that more looks like the traditional Windows Forms look and feel.

Is there any research available on the best color combination's to use for readability, ease of use, and reduced eye strain?

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