As someone in the world of HPC who came from the world of enterprise web development, I'm always curious to see how developers back in the "real world" are taking advantage of parallel computing. This is much more relevant now that all chips are going multicore, and it'll be even more relevant when there are thousands of cores on a chip instead of just a few.

My questions are:

1. How does this affect your software roadmap?
2. I'm particularly interested in real stories about how multicore is affecting different software domains, so specify what kind of development you do in your answer (e.g. server side, client-side apps, scientific computing, etc).
3. What are you doing with your existing code to take advantage of multicore machines, and what challenges have you faced? Are you using OpenMP, Erlang, Haskell, CUDA, TBB, UPC or something else?
4. What do you plan to do as concurrency levels continue to increase, and how will you deal with hundreds or thousands of cores?
5. If your domain doesn't easily benefit from parallel computation, then explaining why is interesting, too.

Finally, I've framed this as a multicore question, but feel free to talk about other types of parallel computing. If you're porting part of your app to use MapReduce, or if MPI on large clusters is the paradigm for you, then definitely mention that, too.

Update: If you do answer #5, mention whether you think things will change if there get to be more cores (100, 1000, etc) than you can feed with available memory bandwidth (seeing as how bandwidth is getting smaller and smaller per core). Can you still use the remaining cores for your application?