This list is in no particular order. Just the 10 best programming podcast that I have found so far.

1. Stack Overflow Podcast -  Jeff Atwood (of codinghorror.com) and Joel Spolsky (of joelonsoftware.com) discuss the development of their new programming community, StackOverflow.com.
   [This Podcast hasn’t been updated in a while, but its always great to hear more from Jeff Atwood]
2. Hanselminutes - Hanselminutes is a weekly audio talk show with noted web developer and technologist Scott Hanselman and hosted by Carl Franklin. Scott discusses utilities and tools, gives practical how-to advice, and discusses ASP.NET or Windows issues and workarounds.
   [This Podcast has recently started talking about random topics like diabetes, plane travel and geek relationship tips.  I am not sure if Scott is trying to move to a more mainstream audience or not]
3. Herding Code - A weekly discussion featuring K. Scott Allen (odetocode.com), Kevin Dente, Scott Koon (lazycoder.com), and Jon Galloway.
   [Great all all-around podcast that I would recommend to all]
4. Deep Fried Bytes - Deep Fried Bytes is an audio talk show with a Southern flavor hosted by technologists and developers Keith Elder and Chris Woodruff. The show discusses a wide range of topics including application development, operating systems and technology in general. Anything is fair game if it plugs into the wall or takes a battery.
   [This is one that just keeps getting better]
5. Dot Net Rocks - .NET Rocks! is an Internet Audio Talk Show for Microsoft .NET Developers.
   [One of the first and usually very high quality content]
6. Connected Show - Connected Show Podcast! A podcast covering new Microsoft technology for the developer community. The show is hosted by Dmitry Lyalin and Peter Laudati.
   [This and Polymorphic are one of my favorite podcast – Dmitry is a great host and would recommend this to all]
7. Polymorphic Podcast - Object oriented development, architecture and best practices in .NET
   [Craig is a ASP.NET MVP and a great presenter. His podcast is great and it could only be better if he recorded it more often]
8. ASP.NET Podcast - Wallace B. (Wally) McClure presents interviews and short technical talks on .NET Technologies.
   [Has great information on ASP.NET of course as well as iPhone Dev]
9. Ruby on Rails Podcast - News and interviews about the Ruby language and the Rails website framework.
   [Even though I am not a Ruby programmer, I’ve found this podcast very interesting]
10. Software Engineering Radio - Software Engineering Radio is a podcast targeted at the professional software developer. The goal is to be a lasting educational resource, not a newscast. Every ten days, a new episode is published that covers all topics software engineering. Episodes are either tutorials on a specific topic, or an interview with a well-known character from the software engineering world. All SE Radio episodes are original content ? we do not record conferences or talks given in other venues. Each episode comprises two speakers to ensure a lively listening experience. SE Radio is an independent and non-commercial organization.
    [Another excellent podcast – I would recommend any programmer add this to his/her drive home]

If I have missed something, please feel free to email me and it might make the 2011 list. =)