I would like a hotkey to Save All in Notepad++ then switch to the browser and refresh the page. I have to do this thousands of times a day and doing the Save All hotkey, then Alt-Tab to the right window, then F5 to refresh again and again, there must be a better solution? I am open to switching editors if there is another that can do this.

I have tried using run commands but the problem is although it allows you to make something like [firefox.exe "current file"], if you come down to wanting to open it at a web address like localhost because it needs to run server side, then you have to manually specify the other part of the string, like [chrome.exe "custom var(web address) / filename"] and it always opens a new tab, then creates lots of clutter. Also, if you are editing an include file then it will try to open that instead of the page you want to see when you use the run command, a refresh would be the only realistic method I can think of using.