We are developing a web-based, commercial point-of-sale application. We'd like the same web site to work well on an Ipad as well a desktop browsers. We're looking for a web framework that makes the site look good on an IPad, but also makes the site work well in a desktop browser such as Chrome, IE, or Firefox on Windows or a Mac.

I found quite a few at 18 Mobile Frameworks and Development Tools for Creating iPhone Apps

Most of them, such as JQTouch, help a web site look and act more like a native IPhone application but they don't emphasize the cross platform/browser experience.

The exception seems to be Sproutcore, which seems to be a full-fledged javascript MVC application framework. I did have trouble getting some of the demos to work under Chrome, but what did work looks good.

What framework(s) have you actually used to develop web sites to work on an Ipad and desktop browser? If you didn't use a framework, how did you get it to work well under both environments?