This blog post sounds specific but most of the troubleshooting tips can be applied to other scenarios:

Troubleshooting Microsoft Message Queuing Issues on Microsoft Lync Server 2010

Microsoft Message Queuing (MSMQ) plays an important role in the Microsoft Lync Server 2010 Monitoring/Archiving server infrastructure: in a distributed network environment, MSMQ is used to transmit data from agents located on other servers (such as Front End Servers) to Monitoring/Archiving servers. The purpose of this article is to help you discover the root cause of any MSMQ problems that you might encounter, and to provide suggested ways to fix those problems.

Microsoft Lync Server is the new name for Microsoft Office Communications Server.

It’s good to see a major product make use of MSMQ – there aren’t many in the public eye (Symantec’s Enterprise Vault comes to mind).