In an effort to debug a Silverlight component on a page in SharePoint I opened the Developer Tools in Internet Explorer.  After choosing the Find > Select Element by Click option my page refreshed for some reason and a small bar appeared at the top of the page reading:

You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page.

After a quick look around the internet, some seemed to be suggesting that you have to disable the Internet Explorer Enhanced Security Configuration (IE ESC) in Server Manager.  Since this is one of the very first things I do when creating a VM, I figured the solution did not apply to me.  However, I decided to go ahead and enable IE ESC and then disable it again to see if that would fix the problem, and it did. 

So if you see that error message in IE, the bar and you've already got IE ESC disabled, you can just enable it and disable it to get rid of the bar.