For about 4-5 months now, I seem to be having this sporadic issue--mainly during our busiest time of the day between 10:30-11:45AM, where all my Windows 2003 web servers in a Microsoft NLB cluster start throwing session state server errors. A sample error is below.

System.Web.HttpException: Unable to make the session state request to the session state server. Please ensure that the ASP.NET State service is started and that the client and server ports are the same.  If the server is on a remote machine, please ensure that it accepts remote requests by checking the value of HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\aspnet_state\Parameters\AllowRemoteConnection.  If the server is on the local machine, and if the before mentioned registry value does not exist or is set to 0, then the state server connection string must use either 'localhost' or '127.0.0.1' as the server name.
   at System.Web.SessionState.OutOfProcSessionStateStore.MakeRequest(StateProtocolVerb verb, String id, StateProtocolExclusive exclusiveAccess, Int32 extraFlags, Int32 timeout, Int32 lockCookie, Byte[] buf, Int32 cb, Int32 networkTimeout, SessionNDMakeRequestResults& results)
   at System.Web.SessionState.OutOfProcSessionStateStore.SetAndReleaseItemExclusive(HttpContext context, String id, SessionStateStoreData item, Object lockId, Boolean newItem)
   at System.Web.SessionState.SessionStateModule.OnReleaseState(Object source, EventArgs eventArgs)
   at System.Web.HttpApplication.SyncEventExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute()
   at System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously)

Now I'm using ASP.NET State service on a centralized back-end Windows 2003 server that all servers communicate to.

I was originally using SQL Server state for a couple years as well prior to having this issue. The problem with SQL wqas that when the issue occurred, it created a blocking situation which essentially impacted all users across all servers. The product company recommended that I use the standard ASP.NET State service as that was what they technically supported. Why this would make a difference is beyond me -- but I had no choice but to try it!

I have attempted to create multiple application pools, adding additional servers, chaning TCP/IP timeout from 20 to 30 seconds, and even calling Microsoft ASP.NET product support, with very little success. I even recommended that they review whether they are using read-only session state instead of read/write per page request -- as I understand that this basically causes every page to make round-trips to state server even if state isn't being used on the page.

Unfortunately, the application is developed by our product company and they insist that it is something with my environment because other clients do not have these sort of issues. However, I've talked to other clients and they tell me when they've seen issues like they, they've basically had to create another web farm. This issue almost seems like I've simply reached some architectural limit within the application...

Microsoft's position on the issue is that the session state needs to be reduced and the returncode being reported back from the state server indicates buffers are full.

To better understand the scope of issues (rather than wait for customers to call and complain), I installed ELMAH and configured it to send me e-mails when unhandled exceptions occur. I basically get 500-1000 e-mails during the time period of high activity!

If any one has any other ideas I could try or better ways to troubleshoot, I'd appreciate it.