When I strace my MySQL process, I keep finding the same error over and over:

setsockopt(240, SOL_IP, IP_TOS, [8], 4) = -1 EOPNOTSUPP (Operation not supported)
futex(0x87ab944, FUTEX_WAKE_OP_PRIVATE, 1, 1, 0x87ab940, {FUTEX_OP_SET, 0,         FUTEX_OP_CMP_GT, 1}) = 1
futex(0x87ab260, FUTEX_WAKE_PRIVATE, 1) = 1
select(13, [10 12], NULL, NULL, NULL)   = 1 (in [12])
fcntl64(12, F_SETFL, O_RDWR|O_NONBLOCK) = 0
accept(12, {sa_family=AF_FILE, path="\246\32629iE"...}, [2]) = 803
fcntl64(12, F_SETFL, O_RDWR)            = 0
getsockname(803, {sa_family=AF_FILE, path="/var/lib/mysql\1"...}, [28]) = 0
fcntl64(803, F_SETFL, O_RDONLY)         = 0
fcntl64(803, F_GETFL)                   = 0x2 (flags O_RDWR)
fcntl64(803, F_SETFL, O_RDWR|O_NONBLOCK) = 0
setsockopt(803, SOL_IP, IP_TOS, [8], 4) = -1 EOPNOTSUPP (Operation not supported)
futex(0x87ab944, FUTEX_WAKE_OP_PRIVATE, 1, 1, 0x87ab940, {FUTEX_OP_SET, 0,     FUTEX_OP_CMP_GT, 1}) = 1
futex(0x87ab260, FUTEX_WAKE_PRIVATE, 1) = 1
select(13, [10 12], NULL, NULL, NULL)   = 1 (in [12])
fcntl64(12, F_SETFL, O_RDWR|O_NONBLOCK) = 0
accept(12, {sa_family=AF_FILE, path="\246\32629iE"...}, [2]) = 240
fcntl64(12, F_SETFL, O_RDWR)            = 0
getsockname(240, {sa_family=AF_FILE, path="/var/lib/mysql\1"...}, [28]) = 0
fcntl64(240, F_SETFL, O_RDONLY)         = 0
fcntl64(240, F_GETFL)                   = 0x2 (flags O_RDWR)
fcntl64(240, F_SETFL, O_RDWR|O_NONBLOCK) = 0
setsockopt(240, SOL_IP, IP_TOS, [8], 4) = -1 EOPNOTSUPP (Operation not supported)

When I look for running mysql processes I don't see anything out of the ordinary.

I figured it might be someplace in my code, so I modified .htaccess to spit out a 502 error to prevent it from loading anything. The error still shows up, just less frequently.

There have been quite a few threads that talk about this error, but no real answer as to how to solve it.

my.conf, as per request:

[mysqld]
#skip-networking
#log-slow-queries
#safe-show-database
#local-infile = 0

log-slow-queries = /var/log/mysql-slow.log
max_connections = 200
query_cache_limit = 128643200
key_buffer_size = 1200144000
low_priority_updates = 1
concurrent_insert = 2
thread_cache_size = 7
query_cache_size = 662144000
table_cache = 1600
table_definition_cache = 1024
long_query_time = 2.5
open_files_limit = 2647
max_connect_errors=999999999