As a relational database programmer (most of the time), I read articles about how relational databases don't scale, and NoSQL solutions such as MongoDB do. As most of the databases I have developed so far have been small to mid scale, I have never had a problem that hasn't been solved by some indexing, query optimization or schema redesign.

What sort of size would I expect to see MySQL struggling with. How many rows?

(I know this is going to depend on the application, and type of data stored. the one that got me thing was basically a genetics database, so would have one main table, with 3 or 4 lookup tables. The main table will contain amongst other things, a chromosome reference, and a position coordinate. It will likely get queried for a number of entries between two potions on a chromosome, to see what is stored there).