How to generate all strings with d-mismatches, python
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Published on 2013-11-06T21:08:49Z
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python
|bioinformatics
I have a following string - "AACCGGTTT" (alphabet is ["A","G","C","T"]). I would like to generate all strings that differ from the original in any two positions i.e.
GAGCGGTTT
^ ^
TATCGGTTT
^ ^
How can I do it in Python?
I have only brute force solution (it is working):
generate all strings on a given alphabet with the same length
append strings that have 2 mismatches with a given string
However, could you suggest more efficient way to do so?
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