I need some way to synchronize 2 drives I have. I want to do this ofter (once a day or so)

There is the main drive that I want to clone/synchronize on a backup hard disk.

The problem is in that there is an open TrueCrypt file mounted as a drive, and its live.

If you don't know what true crypt is, basically you create a file on a hard disk and that file is encrypted. It's constantly open and modified live. Also Its pretty large. 100GB +

I will use freefilesync . There are many tools that can do that.

My question is, is it safe to copy the encrypted file while its open ? Does the software freeze the file in one state and copies it ? Or will I get a corrupted file on the other drive ?

It was not clear to me how windows handles that. I read something about shadow copy, and the software says that it supports this.

Does anyone know something on the matter that can help me ? or some software that will work ok in my scenario ?

Thanks