I need to send an image from a file to a server. The server request the image in a resolution of 2400x2400. What I'm trying to do is: 1) Get a Bitmap using BitmapFactory.decodeFile using the correct inSampleSize. 2) Compress the image in JPEG with a quality of 40% 3) Encode the image in base64 4) Sent to the server I cannot achieve the first step, it throws an out of memory exception. I'm sure the inSampleSize is correct but I suppose even with inSampleSize the Bitmap is huge (around 30 MB in DDMS). Any ideas how can do it? Can I do these steps without created a bitmap object? I mean doing it on filesystem instead of RAM memory. This is the current code: // The following function calculate the correct inSampleSize Bitmap image = Util.decodeSampledBitmapFromFile(imagePath, width,height); // compressing the image ByteArrayOutputStream baos = new ByteArrayOutputStream(); image.compress(Bitmap.CompressFormat.JPEG, 40, baos); // encode image String encodedImage = Base64.encodeToString(baos.toByteArray(),Base64.DEFAULT));