I raised OpenVPN on server for the first time. It worked fine until the server rebooted. The firewall configuration is unchanged. When I tcpdump from tun interface on the server, I always get TCP retransmissions on all TCP packets larger than a few bytes in Android. Using a similar(read: same) configuration on my Linux box from where I'm posting this message now works just fine; no retransmissions, no loss. It did work just fine before the server rebooted. What could possibly cause this? I already tried rebooting Android, it didn't help. Client configuration, used on both Linux PC and Android tablet: dev tun client remote 192.168.0.1 persist-key persist-tun nobind pkcs12 user.p12 mssfix 1480 cipher AES-256-CBC verb 3 1480 is below the mtu of uplink connection on server which is 1492. I tried adding tun-mtu 1480 to Android but that didn't help either.