I installed a fresh copy of Ubuntu 12 desktop then: Installed WINE from the Ubuntu Software Center. Installed WineTricks from the Ubuntu Software Center. When I type the following commands in the terminal: sudo winetricks dotnet40 I get this error message: wine cmd.exe /c echo '%ProgramFiles%' returned empty string If i try the command without sudo winetricks dotnet40 The output is as follows Executing w_do_call dotnet40 Executing load_dotnet40 ------------------------------------------------------ dotnet40 does not yet fully work or install on wine. Caveat emptor. ------------------------------------------------------ Executing mkdir -p /home/vectoruser/.cache/winetricks/dotnet40 mkdir: cannot create directory `/home/vectoruser/.cache/winetricks/dotnet40': Permission denied ------------------------------------------------------ Note: command 'mkdir -p /home/vectoruser/.cache/winetricks/dotnet40' returned status 1. Aborting. ------------------------------------------------------ My current user is vectoruser which i use to logon to Ubuntu The output of ls -ld /home/vectoruser /home/vectoruser/.cache /home/vectoruser/.cache/winetricks Gives: drwxr-xr-x 32 vectoruser vectoruser 4096 Aug 2 19:26 /home/vectoruser drwx------ 19 vectoruser vectoruser 4096 Aug 2 19:25 /home/vectoruser/.cache drwxr-xr-x 2 root root 4096 Aug 2 18:09 /home/vectoruser/.cache/winetricks