Below is my data: Data Here 94/452O Data more 94/4522i Data bla 94/111 Data bla 94/459es Data bla 94/444 items is automatically generated by some previous code but it could come out like: items = ["Data Here 94/452O", "Data more 94/4522i", "Data bla 94/111", "Data bla 94/459es", "Data bla 94/444"] Now currently I'm appending the following: "\n".join(items).replace("4ke", "9") with a few other .replaces however I want it to replace/change the characters on the end of the numbers with a capital letter instead of lowercase... Output: Data Here 94/452O Data more 94/4522I Data bla 94/111 Data bla 94/459ES Data bla 94/444