Memcache is the only important app running on the server Server has 16 cores and 144G RAM Memcache is given 135G Memcache runs at 32 threads Gigabit network, test shows at least 300Mbit/s availability on network port 600 connections 3000 requests per second Say that memcache (memory) usage is at 50% - it's definitely not full As we increase number of requests towards server, requests slow down (from 8ms to 100ms per request) but server load remains 0.00. We suspect this can be solved by adjusting configuration but we don't understand many of the configuration parameters (besides, maybe, the number of threads). Any ideas?