I realy hope some one can help me here cause i search all over the web and nothing comes up.. I allways used PS/2 KB and Mouse and a USB KeyPad (Genius ErgoMedia 500 Gaming Explorer) to play some games, mmorpg, fps, you named, very good whit 11 keys whit possible macros etc etc... Now it comes the problem, i have a USB mouse that have 4 extra buttons, and i need more button, i love buttons.. Well, i plug in the USB mouse and disconectes de PS/2. Everything is ok until i toutch the mouse. If i do so, the ErgoMedia goes off, then on, then i mouse the mouse or press a button and all over again. Yesterday i went buying a new mouse that i liked, a USB mouse too (NPlay whit macros and all that stuff 3600dpi...) Hoping the problem was only whit the other mouse, but no.. It does the exact same thing, ErgoMedia keeps disconecting and conecting everytime i toutch the mouse. What i allready did: Update drivers of both mouses Update drivers of ErgoMedia (no specific drivers(Windows based)) Update drivers of MB Chipset (Actualy no, cause it was up to date allready) Trying other USB Ports (4 Ports back, 4 Ports Front and even 1 Port in 16 card slot device) Disable the "Allows Windows to shut down the energy bla bla" thing in Device Setings. Look up in the Device Setings only apear a problem on the ergomedia (Human interface Device) when i move the damm mouse.. Using Everest to read behavier, everything normal, exepts the disconecting thing, but no errors. Not a power suply, only the ErgoMedia and the mouse are in the USBs, and i allready disable the 16 card reader whit one usb slot to see.. Clean the IRQ registry. Look the entire internet for a fix solution. Help others problems wile looking for a fix for me (Im not a pro but not a completly stupid) Talking to you beggin you to help me as a last resorce... Machine: Acer M3641 Core2Quad 64x Based OS Vista 64b 4GbRAM HD Audio and Graphics I realy hope some one out there knows a fix for this, maybe it´s a simple thing, so simple that i´m to stupid to see that.. Sorry for my bad inglish but i write lot of erros even in my language. Any help will be very welcome. Tanks for ur concern and atention ^^