Other Superuser questions have addressed the issue of adding custom routes to access e.g.: multiple networks of a corporate network through one interface, while accessing the Internet through another interface. So assuming that I have a script to add specific routes when en0 is configured, and a separate script to add specific routes when en1 is configured, is there some way I can trigger those scripts to run automatically when Mac OS X/Darwin starts and configures those interfaces? Back in my Linux days, it was possible to add an option in /etc/network/interfaces along the lines of: iface eth0 inet dhcp up /usr/local/sbin/eth0-routes-up Is there something similar for Mac OS X?