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  • What do you think is the best language for Bioinformatics?

    - by Ben Fossen
    I have done a couple research jobs in Bio-informatics and I have used Matlab for them. Matlab had a lot of powerful tools and was easy to use. I did thinks with genome sequencing and predicting metabolic pathways. I am wondering what other people think is best? or there might not be one specific language but a few that lend themselves best to Bio-informatics work that is math heavy and deals with a large amount of data.

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  • Looking for: C/C++ Regex library that supports Named Captures

    - by user318811
    I'm thinking about writing a small application that will help me mass rename files. I currently use an application named 'RegexRenamer', which (I'm assuming) uses the .NET regex engine. The application is fine, but is sort of clunky. So what I'm looking for is a C/C++ regex library that I can build my custom program off of. Anything that is small and lightweight is preferred (.Net seems heavy). Thanks.

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  • Mathematics - Why is Differential Calculus (MVP) in PHP a tabu?

    - by Email
    Hi I want to do a Mean-Variance-Optimization (Markowitz) but i never found anything written in php that does this. MVP needs differential calculus. Can it be done in php and why arent there any classes/works from universities? For a webapplication (regarding performance) would another language be the better choice to handle heavy calculations? Thanks so much for any help/answer on this

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  • iPhone App is leaking memory; Instruments and Clang cannot find the leak

    - by Norbert
    Hi, i've developed an iPhone program which is kind of an image manipulation program: The user get an UIImagePickerController and selects an image. Then the program does some heavy calculating in a new thread (for responsiveness of the application). The thread has, of course, its own autorelease pool. When calculation is done, the seperated thread signals the main thread that the result can be presented. The app creates a new view controller, pushes it onto the navigation controller. In short: UIImagePickerController new thread (autorelease pool) does some heavy calculation with image data signal to main thread that it's done main thread creates view controller and pushes it onto navigation controller view controller presents image result My program works well, but if I dismiss the navigation controller's top view controller by tapping on the back button and repeat the whole process several times, my app crashes. But only on the device! Instruments cannot find any leaks (except for some minor ones which I don't feel responsible for: thread creation, NSCFString; overall about 10 kB). Even Clang static analyzer tells me that my could seems to be all right. I know that the UIImage class can cache images and objects returned from convenience methods get freed only whet their autorelease pool gets drained. But most of the time I work with CGImageRef and I use UIImage' alloc, init & release methods to free memory as soon as possible. Currently, I don't know how to isolate the problem. How would you approach this problem? Crash Log: Incident Identifier: F4C202C9-1338-48FC-80AD-46248E6C7154 CrashReporter Key: bb6f526d8b9bb680f25ea8e93bb071566ccf1776 OS Version: iPhone OS 3.1.1 (7C145) Date: 2009-09-26 14:18:57 +0200 Free pages: 372 Wired pages: 7754 Purgeable pages: 0 Largest process: _MY_APP_ Processes Name UUID Count resident pages _MY_APP_ <032690e5a9b396058418d183480a9ab3> 17766 (jettisoned) (active) debugserver <ec29691560aa0e2994f82f822181bffd> 107 syslog_relay <21e13fa2b777218bdb93982e23fb65d3> 62 notification_pro <8a7725017106a28b545fd13ed58bf98c> 64 notification_pro <8a7725017106a28b545fd13ed58bf98c> 64 afcd <98b45027fbb1350977bf1ca313dee527> 65 mediaserverd <eb8fe997a752407bea573cd3adf568d3> 319 ptpd <b17af9cf6c4ad16a557d6377378e8a1e> 142 syslogd <ec8a5bc4483638539fa1266363dee8b8> 68 BTServer <1bb74831f93b1d07c48fb46cc31c15da> 119 apsd <a639ba83e666cc1d539223923ce59581> 165 notifyd <2ed3a1166da84d8d8868e64d549cae9d> 101 CommCenter <f4239480a623fb1c35fa6c725f75b166> 161 SpringBoard <8919df8091fdfab94d9ae05f513c0ce5> 2681 (active) accessoryd <b66bcf6e77c3ee740c6a017f54226200> 90 configd <41e9d763e71dc0eda19b0afec1daee1d> 275 fairplayd <cdce5393153c3d69d23c05de1d492bd4> 108 mDNSResponder <f3ef7a6b24d4f203ed147f476385ec53> 103 lockdownd <6543492543ad16ff0707a46e512944ff> 297 launchd <73ce695fee09fc37dd70b1378af1c818> 71 **End**

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  • SQL Server 2005 red herring error "The user does not have permission to perform this action"

    - by Sylvia
    We're getting the error "The user does not have permission to perform this action" during times of heavy load (regularly, when a trim job occurs). The error clears up when the service accessing sql server is restarted, so it's obviously not a real permissions problems. What kind of situations could cause an error like this, when it's not really a permissions problem? Any ideas of good places to start looking? thanks for any insights...

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  • Twitter and Facebook status in

    - by Chris S
    Are there any C# libraries for integrating Facebook status updates and twitter updates (preferably with url shortening) in Monotouch without too much heavy lifting? I know there is a Facebook kit already for objective-C, I really only need status updating however.

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  • Setting Twitter and Facebook statuses

    - by Chris S
    Are there any C# libraries for integrating Facebook status updates and twitter updates (preferably with url shortening) in Monotouch without too much heavy lifting? I know there is a Facebook kit already for objective-C, I really only need status updating however.

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  • C# & ASP.Net - determine linq query generation time

    - by Chris Klepeis
    I'd like to detemine the amount of time it takes for my ASP.Net program to generate certain sql queries using linq.... note - I want the query generation time, not the query execution time. Is this possible, or even feasable (if its usually fast)? My website has some heavy traffic and I want to cover all of my bases.

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  • How should I begin to help projects in Github?

    - by Erik Escobedo
    I'm new to github and I like to help other people with his projects that I find interesting. I know there's a lot of guides in the github place, but I think it could be nice to gather a bunch of real people's experiences. So, I invite you to post about your first experiences in github. Whether you are a not-so-newbie or you are a heavy rock in github comunnity, I think your lines could encourage real newbies like me about entering this great open source community.

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  • What techniques are being used to pass MVC ModelState validation errors back to the client when usin

    - by Jon Erickson
    I'm sort of thinking out loud here, so let me know if I need to clarify... on ajax heavy sites, when using JsonResult to pass information back to the client, what techniques, patterns, best practices are being used to pass ModelState validation errors back to the client? I am using xVal and castle validation on my view models, is there some sort of standard to get jquery validate to display errors coming from ajax responses?

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  • Detect if objects are loaded [Javascript]

    - by Samuel
    I was wondering, is there a way to detect if a certain image / div is loaded? For example when i am loading two heavy images and showing a loading sign at the two places the images will later occupy, is there a way to already display the first image when it's loaded while still loading the second one?

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  • Java fixed memory map

    - by juber
    Hi, Is there a simple, efficient Map implementation that allows a limit on the memory to be used by the map. My use case is that I want to allocate dynamically most of the memory available at the time of its creation but I don't want OutOFMemoryError at any time in future. Basically, I want to use this map as a cache, but but I wanna avoid heavy cache implementations like EHCache. My need is simple (at most an LRU algorithm)

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  • My portfolio site crashes IE 7 and IE 6

    - by Jonathan Branthwaite
    Hi My portfolio site www.jonathanbranthwaite.co.uk uses heavy JQuery - sliding carousel and lightbox navigation. It works fine in Firefox and Safari, and from what I gather in IE 8. Does anyone know if the code is incorrect or if there is something making it crash, or is this just because of alot of JQuery. Any help would be appreciated. Thanks Jonathan

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  • Suitable compiled language for new project [closed]

    - by Toby
    Hello, I'm about to develop some commercial software that will run on OSX and Linux. The program will be doing some heavy string manipulation, base64 encoding, zlib compression and may require http libraries in the future. Does anyone have a suggestion? Many thanks in advance, Toby.

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  • Flash (ActionScript 3): how to build a remoting application

    - by Lothar
    Hi, I'm looking for examples (code) of applications that uses Flash (NOT Flex) and Remoting classes for ActionScript 3 (NetConnection). Once there was ARP, a repository of code of this kind, but it seems there is not anymore. I'm trying to figure out how to build an applications that makes heavy use of calls to WebORB and responders. I need an architect point of view, NOT a sample of communication between parts, but a real world scenario.

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  • Is there a way to identify which web framework is used in a site?

    - by ragu.pattabi
    Whenever I come across a cute website, I am always curious to know which web framework was used by its developers? Being a novice in web development, a look at the page source doesn't give any clue. Any way(s) to get this information? If possible, may be with a bit of Ruby magic, I can figure out things like: which is the most/least used framework for my favorite sites, audio/video heavy sites, etc.

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  • I'm tired of JButtons, how can I make a nicer GUI in java ?

    - by Jules Olléon
    So far I've only build "small" graphical applications, using swing and JComponents as I learned at school. Yet I can't bear ugly JButtons anymore. I've tried to play with the different JButton methods, like changing colors, putting icons etc. but I'm still not satisfied. How do you make a nicer GUI in java ? I'm looking for not-too-heavy alternatives (like, without big frameworks or too complicated libraries).

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  • Compiling .xsl files into .class files

    - by Alex Ciminian
    I'm currently working on a Java web project (Spring) which involves heavy use of xsl transformations. The stylesheets seldom change, so they are currently cached. I was thinking of improving performance by compiling the xsl-s into class files so they wouldn't have to be interpreted on each request. I'm new to Java, so I don't really know the ecosystem that well. What's the best way of doing this (libraries, methods etc.)? Thanks, Alex

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