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• ASP.NET 2.0 and COM Port Communication

  - by theaviator

  ASP.NET 2.0 and COM Port Communication Hello Guys, I have a managed DLL which communicates with the devices attached on COM/Serial ports. The desktop Winforms application sends requests on ports and receives/stores data in memory. In Winforms app I have added a reference to DLL and I am using the methods. This works well. Now, there is a situation where I need to show this data from serial/com port on a web-page. And also users should be able to send requests to the ports using this DLL. I have made a web app in ASP.NET (2.0). Added a reference to the DLL. I am able to use this DLL, the DLL communicates on the COM upon button click on web-page and also the response is shown on web page. However I am not happy with the approach and strongly feel that this is a bad approach. Also the development server crashes after 3 -4 requests. What is the best approach in this scenario. If I use a windows service then how would my ASP.net app will communicate with the Weindows service. Or can this be easily done using WCF. I have not used WCF any time nor any of .net remoting technique. Please suggest me the best architecture in this scenario. Thank you

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• Linq-to-sql Add item and a one-to-many record at once

  - by Oskar Kjellin

  I have a function where I can add articles and users can comment on them. This is done with a one to many relationship like= "commentId=>ArticleId". However when I try to add the comment to the database at the same time as I add the one to many record, the commentId is not known. Like this code: Comment comment = new Comment(); comment.Date = DateTime.UtcNow; comment.Text = text; comment.UserId = userId; db.Comments.InsertOnSubmit(comment); comment.Articles.Add(new CommentsForArticle() { ArticleId = articleId, CommentId = comment.CommentId }); The commentId will be 0 before i press submit. Is there any way arround not having to submit in between or do I simply have to cut out the part where I have a one-to-many relationship and just use a CommentTable with a column like "ArticleId". What is best in a performance perspective? I understand the underlying issue, I just want to know which solution works best.

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• How to improve performance of non-scalar aggregations on denormalized tables

  - by The Lazy DBA

  Suppose we have a denormalized table with about 80 columns, and grows at the rate of ~10 million rows (about 5GB) per month. We currently have 3 1/2 years of data (~400M rows, ~200GB). We create a clustered index to best suit retrieving data from the table on the following columns that serve as our primary key... [FileDate] ASC, [Region] ASC, [KeyValue1] ASC, [KeyValue2] ASC ... because when we query the table, we always have the entire primary key. So these queries always result in clustered index seeks and are therefore very fast, and fragmentation is kept to a minimum. However, we do have a situation where we want to get the most recent FileDate for every Region, typically for reports, i.e. SELECT [Region] , MAX([FileDate]) AS [FileDate] FROM HugeTable GROUP BY [Region] The "best" solution I can come up to this is to create a non-clustered index on Region. Although it means an additional insert on the table during loads, the hit isn't minimal (we load 4 times per day, so fewer than 100,000 additional index inserts per load). Since the table is also partitioned by FileDate, results to our query come back quickly enough (200ms or so), and that result set is cached until the next load. However I'm guessing that someone with more data warehousing experience might have a solution that's more optimal, as this, for some reason, doesn't "feel right".

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• Javascript/PHP and timezones

  - by James

  Hi, I'd like to be able to guess the user's timezone offset and whether or not daylight savings is being applied. Currently, the most definitive code that I've found for this is here: http://www.michaelapproved.com/articles/daylight-saving-time-dst-detect/ So this gives me the offset along with the DST indicator. Now, I want to use these in my PHP scripts in order to ouput the local date/time for the user....but what's best for this? I figure I have 2 options: a) Pick a random timezone which has the same offset and DST setting from the output of timezone_abbreviations_list(). Then call date_timezone_set() with this in order to apply the correct treatment to the time. b) Continue treating the date as UTC but just do some timestamp addition to add the appropriate number of hours on. My feeling is that option B is the best way. The reason for this is that with A, I could be using a timezone which although correct in terms of offset/dst, may have some obscur rules in place behind the scene that could give surprising results (I don't know of any but nonetheless I don't think I can rule it out). I'd then re-check the timezone using Javascript at the start of each session in order to capture when either the user's timezone changes (very unlikely) or they pass in to the DST period. Sorry for the brain dump - I'm really just after some sort of reassurance that the approaches above are valid. Thanks, James.

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• Great examples of self-paced labs and exercises

  - by Mayo

  It is probably a safe bet that many of us are what they call Tactile / Kinesthetic Learners meaning that we learn best when we are physically doing something as opposed to listening to an online tutorial or reading a book. My goal with this question is to derive a list of books or online resources that serve as superb examples of self-paced programming labs and exercises. For example, I was extremely impressed with the SportsStore exercise in Steven Sanderson's Pro ASP.NET MVC Framework. The exercise spanned multiple chapters and gradually introduced new topics. I was also impressed with the materials associated with the Windows Azure Boot Camp. The demos and lab materials, accessible through the website, allow us to practice and reinforce what we can read about in articles and books. Please list any examples you might have, one per submission, below. The question is language/platform agnostic. Suggestions can be generic or specific to a given technology (PHP, SQL Server, Azure, Flash, Objective C, etc.). I only ask that the answers pertain to labs and exercises that relate to programming. My hope is that the best answers will float to the top allowing developers to review the top answers and find another programming topic that can be learned through example.

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• Dealing with Time Zones

  - by RavIncredible

  Hi All, I need some guidance with one of my project requirements, I am developing an application which has to deal with various time zones. Scenario: User 1 is from India, so his time zone would be GMT+05:30 User 2 is from UK, so his time zone would be GMT+01:00 If the User 1 sends a message to User 2, I want to show the Message Sent/Received Time as per the user’s time zone. For example User 1 sends a message at 6:30 Indian time, when User 2 would view the message it would show as 2:00 UK time. Here goes my question, whenever I save the message should I convert it to GMT+00, so all my base times stamps are the same and then later when I display the message, I convert it back to User specific time zone. Would this be complex? Is this the best way of doing this? I like to get views for both saving and displaying, also when I should do the time conversion from optimization point of view. I would need do deal with any/all timezones. I am developing this application with PHP and MySQL and I am aware of timezone conversion method come with both PHP and MySQL. I am just trying to figure out the best way of doing this. Look forward to have all valuable suggestions. Note : As of now I am not much worried with day/light savings. Thanks Ravi

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• Passing arguments to objects created using the new operator?

  - by Abhijit

  Hi guys, I have a small C++ problem to which I don't know the best solution. I have two classes A and B as follows: class A { int n; B* b; public: A(int num): n(num) { b = new B[n]; for (int i = 0; i < n; i++) { b[i].setRef(this); } } ~A() { delete [] b; } }; class B { A* a; public: B() { } B(A* aref) { a = aref; } void setRef(A* aref) { a = aref; } }; I am creating an object of class A by passing to its constructor the number of objects of class B I want to be created. I want every object of class B to hold a pointer to the class A object that creates it. I think the best way to do this would be by passing the pointer to the class A object as a constructor argument to the class B object. However, since I'm using the new operator, the no-args constructor for class B is called. As a result, the only solution I can see here is calling the setRef(A*) method for every object of class B after it has been constructed using the new operator. Is there a better solution/design pattern that would be more applicable here? Would using placement new for class B be a better solution? Thanks in advance for your help.

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• IList<Item> Collection Class accessing database

  - by Mike

  Hi, I have a database with Users. Users have Items. These Items can change actively. How do you access the items in a collection type format? For the user, I fill all the user properties at the time of instantiation. If I load the user's items at the time of the instantiation, and the items change, they will have old data. I was thinking, maybe I need an ItemCollection class and have that a field/property apart of the user class, that way to traverse all the user's items I could use a foreach loop. So, my question is, what is the best practice/best way of accessing the items from a database using some sort of collection? On accessing the particular Item, it needs to get the latest database information, and when the user does do a foreach loop, the latest item information must be available. I.e. What I'm trying to do Console.WriteLine(User.Items[3].ID); returns 5. //this updates the item information and saves it to the database. User.Items[3].ID = 13; //Add a new item to the database. User.Items.Add(new Item { id = 17}); foreach (Item item in User.Items) { //this would traverse all items in the database. //not some cached copy at the time of instantiation of the user. }

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• Umbraco template issues

  - by bomortensen

  Hi fellow Umbraco users, I'm currently building my first umbraco website and since I'm completely new to umbraco I've already ran into a problem which I'm sure is pretty straight-forward to do. That said, I'm by no means a beginner when it comes to building sites that run on a (open source) CMS as I've been using Joomla! since it was called Mambo. Anyway, the site I'm building is here: my site What I want to do is to have some content in the white box that changes when you mouseover/hover one of the menu items. Also that content has to stay "active" when you've clicked on a link (i.e. if you click on "Profile" I need to highlight the Profile menu item with the gray color and the white boxs content needs to be what would be related to the Profile menu item. How do I go about this? What would be the best practice when it comes to showing multiple content on a site? I've watched the video about multiple Content Place Holders, but I never really got it to work. I can't get a page to display in the NavigationPlaceHolder (the placeholder I put in the white box), but thats because the actual page is Frontpage.aspx and not WhateverIsInThenavigationPlaceHolder.aspx. If I go to the mysite.dk/WhateverIsInTheNavigationPlaceHolder.aspx it shows up fine. What have I missed here? :) Thanks in advance! If my question is not clear in some ways, please tell me and I will try to explain it better. All the best, Bo

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• DAL Layer : EF 4.0 or Normal Data access layer with Stored Procedure

  - by Harryboy

  Hello Experts, Application : I am working on one mid-large size application which will be used as a product, we need to decide on our DAL layer. Application UI is in Silverlight and DAL layer is going to be behind service layer. We are also moving ahead with domain model, so our DB tables and domain classes are not having same structure. So patterns like Data Mapper and Repository will definitely come into picture. I need to design DAL Layer considering below mentioned factors in priority manner Speed of Development with above average performance Maintenance Future support and stability of the technology Performance Limitation : 1) As we need to strictly go ahead with microsoft, we can not use NHibernate or any other ORM except EF 4.0 2) We can use any code generation tool (Should be Open source or very cheap) but it should only generate code in .Net, so there would not be any licensing issue on per copy basis. Questions I read so many articles about EF 4.0, on outset it looks like that it is still lacking in features from NHibernate but it is considerably better then EF 1.0 So, Do you people feel that we should go ahead with EF 4.0 or we should stick to ADO .Net and use any code geneartion tool like code smith or any other you feel best Also i need to answer questions like what time it will take to port application from EF 4.0 to ADO .Net if in future we stuck up with EF 4.0 for some features or we are having serious performance issue. In reverse case if we go ahead and choose ADO .Net then what time it will take to swith to EF 4.0 Lastly..as i was going through the article i found the code only approach (with POCO classes) seems to be best suited for our requirement as switching is really easy from one technology to other. Please share your thoughts on the same and please guide on the above questions

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• Using Javascript to flip flop a textbox's readonly flag

  - by Velika

  I have a frame with several radio buttons where the user is supposed to select the "Category" that his Occupation falls into and then unconditionally also specify his occupation. If the user selects "Retired", the requirement is to prefill "Retired" in the "Specify Occupation" text box and to disable it to prevent it from being changed. The Specify Occupation text box should also no longer be a tab stop. If the user selects a radio button other than Retired the Specify Occupation text box should be enabled and once again in the normal tab sequence. Originally, I was setting and clearing the disabled property on the Specify occupation textbox, then I found out that, upon submitting the form, disabled fields are excluded from the submit and the REQUIRED validator on the Specify Occupation textbox was being raised because the textbox was being blanked out. What is the best way to solve this? My approach below was to mimic a disabled text box by setting/resetting the readonly attribute on the text box and changing the background color to make it appear disabled. (I suppose I should be changing the forecolor instead of teh background color). Nevertheless, my code to make the textbox readonly and to reset it doesn't appear to be working. function OccupationOnClick(sender) { debugger; var optOccupationRetired = document.getElementById("<%= optOccupationRetired.ClientId %>"); var txtSpecifyOccupation = document.getElementById("<%= txtSpecifyOccupation.ClientId %>"); var optOccupationOther = document.getElementById("<%= optOccupationOther.ClientId %>"); if (sender == optOccupationRetired) { txtSpecifyOccupation.value = "Retired" txtSpecifyOccupation.readonly = "readonly"; txtSpecifyOccupation.style.backgroundColor = "#E0E0E0"; txtSpecifyOccupation.tabIndex = -1; } else { if (txtSpecifyOccupation.value == "Retired") txtSpecifyOccupation.value = ""; txtSpecifyOccupation.style.backgroundColor = "#FFFFFF"; txtSpecifyOccupation.readonly = ""; txtSpecifyOccupation.tabIndex = 0; } } Can someone provide a suggest for the best way to handle this scenario and porovide a tweek to the code above to fix the setting/resetting on the readonly property?

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• What's the most concise cross-browser way to access an <iframe> element's window and document?

  - by Bungle

  I'm trying to figure out the best way to access an <iframe> element's window and document properties from a parent page. The <iframe> may be created via JavaScript or accessed via a reference stored in an object property or a variable, so, if I understand correctly, that rules out the use of document.frames. I've seen this done a number of ways, but I'm unsure about the best approach. Given an <iframe> created in this way: var iframe = document.createElement('iframe'); document.getElementsByTagName('body')[0].appendChild(iframe); I'm currently using this to access the document, and it seems to work OK across the major browsers: var doc = iframe.contentWindow || iframe.contentDocument; if (doc.document) { doc = doc.document; } I've also see this approach: var iframe = document.getElementById('my_iframe'); iframe = (iframe.contentWindow) ? iframe.contentWindow : (iframe.contentDocument.document) ? iframe.contentDocument.document : iframe.contentDocument; iframe.document.open(); iframe.document.write('Hello World!'); iframe.document.close(); That confuses me, since it seems that if iframe.contentDocument.document is defined, you're going to end up trying to access iframe.contentDocument.document.document. There's also this: var frame_ref = document.getElementsByTagName('iframe')[0]; var iframe_doc = frame_ref.contentWindow ? frame_ref.contentWindow.document : frame_ref.contentDocument; In the end, I guess I'm confused as to which properties hold which properties, whether contentDocument is equivalent to document or whether there is such a property as contentDocument.document, etc. Can anyone point me to an accurate/timely reference on these properties, or give a quick briefing on how to efficiently access an <iframe>'s window and document properties in a cross-browser way (without the use of jQuery or other libraries)? Thanks for any help!

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• Getting a users Facebook profile url

  - by Greg Pabst

  I am creating a registry site so similar people can find each other easily. I don't want to use Facebook Connect as the primary log in method or use Facebook to store their information. I'll be creating a database on my end to store that info. For security reasons I won't be displaying the users address, phone number or email address so I wanted to provide the next best way for people to connect with each other, this is where Facebook comes in. Normally I would just ask them to type their Facebook URL in a text box but I don't think most people know what their url is which is why I think I need to use Facebook Connect. So here is my idea..when the users signs up there is a check box that when checked signifies they are allowing people to find them on Facebook. I assume once they click the register button that a Facebook Connect popup will show up asking for permission to access their Facebook account. When they "allow" it, then I can get their profile url. All I need is their Facebook profile url, I don't want any other Facebook features or information. Is Facebook Connect the best thing to use for this scenario? Is there an easier way? Several months ago on the Facebook Connect site their used to be examples of doing this, but all the documentation has been rearranged and changed and I can't seem to find the information. Any help you can provide would be great!

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• Latex: Convert "Comment" into "Marginal Note"

  - by diegos

  Hi, using LyX I'm trying to convert the "comments" into "marginal notes". I tried several things but without luck. The best shot was like this: \makeatletter \@ifundefined{comment}{}{% \renewenvironment{comment}[1]% {\begingroup\marginpar{\bgroup#1\egroup}}% {\endgroup}} \makeatother or like this: \@ifundefined{comment}{}{% \renewenvironment{comment}% {\marginpar{}% {}}% But what I get is only the first character of the text converted. Like in this image: IMAGE MARGINAL NOTE I searched a lot trying to find how to solve this but without luck. I found the explanation of what is happening: Unexpected Output Only one character is in the new font You thought you changed font over a selection of text, but only the first character has come out in the new font. You have most probably used a command instead of a declaration. The command should take the text as its argument. If you don't group the text, only the first character will be passed as the argument. What I don't know and wasn't able to find is how to group the text. Hope someone could help me :-) Many thanks. Best Regards, Diego (diegostex)

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• Communication between modules

  - by David Elentok

  I have an application that consists from the following three modules: Search (to search for objects) List (to display the search results) Painter (to allow me to edit objects) - this module isn't always loaded (Each object is a figure that I can edit in the painter). When I open an object in the painter it's added to the objects that are already in the painter and I can move it and alter it. I'm using an object similar to the EventAggregator to communicate between the modules. For example, to show the search results I publish a "ShowList" event that is caught by the List module (I'm not sure this is the best way to do this, if anyone has better idea please comment...). One of the features of the search module requires it to get the selected object in the painter (if the painter is available), and I'm not sure what would be the best way to do that... I thought of these solutions: Whenever the selected object in the painter changes it will publish a "PainterSelectedObjectChanged" event which will be caught by the search module and stored for later use. When the selected object is needed by the search module it will publish a "RequestingPainterSelectedObject" event which will be caught by the painter module. The painter module will then set the "SelectedObject" property in the EventArgs object, and when the publish is complete and we're back in the search module we will have the painter's selected object in the EventArgs object. What do you think? what is the right way to do this?

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• NHibernate: how to handle entity-based validation using session-per-request pattern, without control

  - by Seth Petry-Johnson

  What is the best way to do entity-based validation (each entity class has an IsValid() method that validates its internal members) in ASP.NET MVC, with a "session-per-request" model, where the controller has zero (or limited) knowledge of the ISession? Here's the pattern I'm using: Get an entity by ID, using an IFooRepository that wraps the current NH session. This returns a connected entity instance. Load the entity with potentially invalid data, coming from the form post. Validate the entity by callings its IsValid() method. If valid, call IFooRepository.Save(entity). Otherwise, display error message. The session is currently opened when the request begins and flushed when the request ends. Since my entity is connected to a session, flushing the session attempts to save the changes even if the object is invalid. What's the best way to keep validation logic in the entity class, limit controller knowledge of NH, and avoid saving invalid changes at the end of a request? Option 1: Explicitly evict on validation failure, implicitly flush: if the validation fails, I could manually evict the invalid object in the action method. If successful, I do nothing and the session is automatically flushed. Con: error prone and counter-intuitive ("I didn't call .Save(), why are my invalid changes being saved anyways?") Option 2: Explicitly flush, do nothing by default: By default I can dispose of the session on request end, only flushing if the controller indicates success. I'd probably create a SaveChanges() method in my base controller that sets a flag indicating success, and then query this flag when closing the session at request end. Pro: More intuitive to troubleshoot if dev forgets this step [relative to option 1] Con: I have to call IRepository.Save(entity)' and SaveChanges(). Option 3: Always work with disconnected objects: I could modify my repositories to return disconnected/transient objects, and modify the Repo.Save() method to re-attach them. Pro: Most intuitive, given that controllers don't know about NH. Con: Does this defeat many of the benefits I'd get from NH?

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• What is the fastest, most efficient way to get up to speed on a new technology?

  - by SLC

  My current job involves working with a huge number of technologies, most of which are very niche and unheard of. In some cases I have to write something about the technology, or with the technology, such as some lessons, examples, or tutorials, on behalf of the developer of that technology or someone that is backing it. When I get told to learn about a new technology, my first port of call is to check our internal library, and then look on amazon for a book on the subject. Failing that, or if the project is too small to warrant a purchase, I hit up google and youtube. However the results of randomly googling what I want to learn are hit and miss. Some days, I can find everything I want to know in a series of lessons or videos, and it's no problem. Other times, I can find almost nothing, and I really have to piece together things from sites. The result is that there are various resources out there, videos, interactive lessons, tutorials, books etc. but when I need to learn something fast, I often don't know the best way to go about it. It's not about fun, because I don't always have the luxury of working my way through a 600 page textbook named "A Complete Guide To Technology X", I have to deliver results quickly. One of the examples I'd like to use is ASP.NET MVC 2 which is something I have been told to learn. I grabbed a book on MVC 1 to refresh my knowledge, but googling it does't produce much useful information. I've seen a ton of ScottGu's tutorials on it, but they are mostly feature presentations, and some date back almost a year. The same applies to channel 9 and there are no books out yet on amazon. My question therefore has two parts, the first asks, "Where are the best places to look to get the information needed to learn a new technology?" and the second asks "What is the most efficient way to use such resources to learn a new technology?"

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• Caching sitemaps in django

  - by michuk

  I implemented a simple sitemap class using django's default sitemap app. As it was taking a long time to execute, I added manual caching: class ShortReviewsSitemap(Sitemap): changefreq = "hourly" priority = 0.7 def items(self): # try to retrieve from cache result = get_cache(CACHE_SITEMAP_SHORT_REVIEWS, "sitemap_short_reviews") if result!=None: return result result = ShortReview.objects.all().order_by("-created_at") # store in cache set_cache(CACHE_SITEMAP_SHORT_REVIEWS, "sitemap_short_reviews", result) return result def lastmod(self, obj): return obj.updated_at The problem is that memcache allows only max 1MB object. This one was bigger that 1MB, so storing into cache failed: >7 SERVER_ERROR object too large for cache The problem is that django has an automated way of deciding when it should divide the sitemap file into smalled ones. According to the docs (http://docs.djangoproject.com/en/dev/ref/contrib/sitemaps/): You should create an index file if one of your sitemaps has more than 50,000 URLs. In this case, Django will automatically paginate the sitemap, and the index will reflect that. What do you think would be the best way to enable caching sitemaps? - Hacking into django sitemaps framework to restrict a single sitemap size to, let's say, 10,000 records seems like the best idea. Why was 50,000 chosen in the first place? Google advice? random number? - Or maybe there is a way to allow memcached store bigger files? - Or perhaps onces saved, the sitemaps should be made available as static files? This would mean that instead of caching with memcached I'd have to manually store the results in the filesystem and retrieve them from there next time when the sitemap is requested (perhaps cleaning the directory daily in a cron job). All those seem very low level and I'm wondering if an obvious solution exists...

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• Managing/Storing complex application form

  - by mickyjtwin

  I am developing an online application form, which can be of two categories, either domestic/international. Each different type has commong questions, and also specific questions. They are approx 6 pages/steps of questions. The application form can also be saved at the end of each step, and can be completed at a later date. Some questions will vary depending on answers to previous questions, so there are some complex business rules. In terms of storage of results, would it be best to store the answers in and XML field in SQL? What would be the best way to reference a question to an answer. There is no need for the form to be dynamic in rendering questions etc. e.g. <Application id="123" type="Domestic"> <Answers> <EmailAddress>[email protected]</EmailAddress> <HomePhone>555-5555</HomePhone> <Suburb>MySuburb</Suburb> <Guardians> <Guardian type="Mother"> <FirstName>Mom</FirstName> </Guardian> </Guardians> <Answers> </Application>

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• How to customize RESTful Routes in Rails (basics)

  - by viatropos

  I have read through the Rails docs for Routing, Restful Resources, and the UrlHelper, and still don't understand best practices for creating complex/nested routes. The example I'm working on now is for events, which has_many rsvps. So a user's looking through a list of events, and clicks register, and goes through a registration process, etc. I want the urls to look like this: /events /events/123 # possible without title, like SO /events/123/my-event-title # canonical version /events/my-category/123/my-event-title # also possible like this /events/123/my-event-title/registration/new ... and all the restful nested resouces. Question is, how do I accomplish this with the minimal amount of code? Here's what I currently have: map.resources :events do |event| event.resources :rsvps, :as => "registration" end That gets me this: /events/123/registration What's the best way to accomplish the other 2 routes? /events/123/my-event-title # canonical version /events/my-category/123/my-event-title # also possible like this Where my-category is just an array of 10 possible types the event can be. I've modified Event#to_param to return "#{self.id.to_s}-#{self.title.parameterize}", but I'd prefer to have /id/title with the whole canonical-ness

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• Domain Transfer Protection - need advice

  - by Jack

  Hey, I am about to purchase a domain name for a bit of money. I do not personally know the person who I am purchasing the domain name from, we have only chatted via email. The proposed process for the transfer is: The owner of the domain lowest the domain name security and emails me the domain password, I request the transfer After the request, I transfer the money via PayPal When the money has been cleared the current domain name owner confirms the transfer via the link that he receives in that email I wait for it to be transferred. The domain is currently registered with DirectNIC - http://www.directnic.com/ Is this the best practice? Seeing I am paying a bit of money for this domain name, I am worried that after the money has been cleared that I won't see the domain name or hear from the current domain name owner again. Is there a 'domain governing body' which I can report to if this is the case? Is the proposed transfer process the best solution? Any advice would be awesome. Thanks! Jack

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• How can I apply a PSSM efficiently?

  - by flies

  I am fitting for position specific scoring matrices (PSSM aka Position Specific Weight Matrices). The fit I'm using is like simulated annealing, where I the perturb the PSSM, compare the prediction to experiment and accept the change if it improves agreement. This means I apply the PSSM millions of times per fit; performance is critical. In my particular problem, I'm applying a PSSM for an object of length L (~8 bp) at every position of a DNA sequence of length M (~30 bp) (so there are M-L+1 valid positions). I need an efficient algorithm to apply a PSSM. Can anyone help improve performance? My best idea is to convert the DNA into some kind of a matrix so that applying the PSSM is matrix multiplication. There are efficient linear algebra libraries out there (e.g. BLAS), but I'm not sure how best to turn an M-length DNA sequence into a matrix M x 4 matrix and then apply the PSSM at each position. The solution needs to work for higher order/dinucleotide terms in the PSSM - presumably this means representing the sequence-matrix for mono-nucleotides and separately for dinucleotides. My current solution iterates over each position m, then over each letter in word from m to m+L-1, adding the corresponding term in the matrix. I'm storing the matrix as a multi-dimensional STL vector, and profiling has revealed that a lot of the computation time is just accessing the elements of the PSSM (with similar performance bottlenecks accessing the DNA sequence). If someone has an idea besides matrix multiplication, I'm all ears.

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• PHP CodeIgniter Framework - Thoughts on developing with it?

  - by Sootah

  I've been reviewing different frameworks to use for my next couple of major web applications, and after days of research am almost set on using CodeIgniter. The reason I'm leaning towards CI is that so far it looks to be the best suited for me. It doesn't require constant command-line access (I am currently using shared hosting; the projects do not warrant a dedicate server yet), nothing special has to be installed on the server running it (you just upload the framework to the root of whatever your developing), and they appear to have some excellent documentation, videos, and tutorials on how to get started. Do any of you have experience with CodeIgniter? If so, what is your opinion of it and its features? What had you developed with it, and what types of applications is it best suited to create? I certainly don't want to get into a situation where I'm trying to bend a framework to do something that it isn't well-suited for. Both of my projects will be database-driven apps that will require user registration, the ability to manipulate data that is specific to their account (their posts, listings, user account details, etc), amongst other things. Also, if you have any other PHP framework suggestions, I am open to them. Thanks in advance for your help! -Sootah

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• Bi-directional view model syncing with "live" collections and properties (MVVM)

  - by Schneider

  I am getting my knickers in a twist recently about View Models (VM). Just like this guy I have come to the conclusion that the collections I need to expose on my VM typically contain a different type to the collections exposed on my business objects. Hence there must be a bi-directional mapping or transformation between these two types. (Just to complicate things, on my project this data is "Live" such that as soon as you change a property it gets transmitted to other computers) I can just about cope with that concept, using a framework like Truss, although I suspect there will be a nasty surprise somewhere within. Not only must objects be transformed but a synchronization between these two collections is required. (Just to complicate things I can think of cases where the VM collection might be a subset or union of business object collections, not simply a 1:1 synchronization). I can see how to do a one-way "live" sync, using a replicating ObservableCollection or something like CLINQ. The problem then becomes: What is the best way to create/delete items? Bi-directinal sync does not seem to be on the cards - I have found no such examples, and the only class that supports anything remotely like that is the ListCollectionView. Would bi-directional sync even be a sensible way to add back into the business object collection? All the samples I have seen never seem to tackle anything this "complex". So my question is: How do you solve this? Is there some technique to update the model collections from the VM? What is the best general approach to this?

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• archiving strategies and limitations of data in a table

  - by Samuel

  Environment: Jboss, Mysql, JPA, Hibernate Our web application will be catering to a large amount of users (~ 1,000,000) and there are a lots of child table where user specific data are stored (e.g. personal, health, forum contributions ...). What would be the best practice to archive user & user specific information. [a] Would it be wise to move the archived user & user specific information to their respective tables within the same database (e.g. user_archive, user_forum_comments_archive ...) OR [b] Would you just mark the database entries with a flag in the original table(s) and just query only non archived entries. We have a unique constraint on User.loginid, how do you handle this requirement if the users are archived via 1-[a] (i.e if a user with loginid 'samuel' gets moved into the archive table and if a new user gets added with the same name in the original table, how would you prevent this. What would be the best strategy to address the unique key constraints. We have a requirement to selectively archive records and bring it back if necessary, will you rely on database tools are would you handle this via your persistence APIs exposed by the JPA entity model.

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