I was able to use Photoshop CS5 perfectly on Ubuntu 11.10. After upgraded to 12.04 I've noticed that when I try to use brush tool in by dragging the left mouse button I cannot get continous effect on photos. It only effects the area I click with mouse. In the screenshot all the time I was holding the left mouse button but it only affected the image once, creating dots instead of lines. At first I thought its something with Wine. I reinstalled it then deleted Photoshop in my ApplicationData folder (Windows keeps user software options in this folder). None of these worked. I tried on my laptop and this strange problem exists there too.