Hi, We use the asp.net UpdatePanel and the ScriptManager/ScriptManagerProxy for ajax related functionality; reducing full page refreshes and calling WCF Services respectively. we also use jQuery and plugins for some parts of the UI. We have had some issues with javascript library related conflicts, but have come across some posts indicating that there is a lot more overhead using the UpdatePanel. I have found some limited reference to UFrame: http://www.codeproject.com/KB/aspnet/uframe.aspx www.codeplex.com/uframe Is this a commercially viable replacement for the asp.net UpdatePanel? We use a ScriptManagerProxy to reference WCF services and easily create and use a proxy to call the various WCF service methods. Would using jQuery ajax be a more efficient solution here? We have got this working well on various browsers but now seem to be getting some security related issues (as seen in FF Firebug: Access to restricted URI denied" code: "1012) which seem to have started since using jQuery a lot more. Is it possible/viable to not use ASP.NET Ajax at all?