I've a TextBlock that looks like so:

<TextBlock Text="{Binding Name}" />

This is inside a <Canvas> with the DataContext set to MyClient which is in the ViewModel:

public Client MyClient { get; private set; } // This is a RIA Entity, hence supports INotifyPropertyChanged

public ViewModel() {
    MyClient = new Client();
    LoadOperation<Client> loadClient = RiaContext.Load<Client>(RiaContext.GetClientsQuery());
    loadClient.Completed += new EventHandler(loadClient_Completed);
}

void loadClient_Completed(object sender, EventArgs e) {
    MyClient = DB.Clients.Single();
}

Setting MyClient like the above does not raise the PropertyChanged event. As such the UI is never updated.