Question: what's the best way to accomplish following. I have to come up with unique ID for each networked client, such that:

• it (ID) should persist once client software is installed on target computer, and should continue to persist if software is re-installed on same computer and same OS installment,
• it should not change if hardware configuration is modified in most ways (except changing the motherboard)
• When hard drive with client software installed is cloned to another computer with identical hardware configuration (or, as similar as possible), client software should be aware of that change.

A little bit of explanation and some back-story:

This question is basically age old question that also touches topic of software copy-protection, as some of mechanisms used in that area are mentioned here. I should be clear at this point that I'm not looking for a copy-protection scheme. Please, read on. :)

I'm working on a client-server software that is supposed to work in local network. One of problems I have to solve is to identify each unique client in network (not so much of a problem), so that I can apply certain attributes to every specific client, retain and enforce those attributes during deployment lifetime of a specific client.

While I was looking for a solution, I was aware of following:

• Windows activation system uses some kind of heavy fingerprinting mechanism, that is extremely sensitive to hardware modifications,
• Disk imaging software copies along all Volume IDs (tied to each partition when formatted), and custom, uniquely generated IDs during installation process, during first run, or in any other way, that is strictly software in its nature, and stored in registry or on hard drive, so it's very easy to confuse two

Obvious choice for this kind of problem would be to find out BIOS identifiers (not 100% sure if this is unique through identical motherboard models, though), as that's the only thing I can rely on, that isn't duplicated, transferred by cloning, and that can't be changed (at least not by using some user-space program). Everything else fails as either being not reliable (MAC cloning, anyone?), or too demanding (in terms that it's too sensitive to configuration changes).

Am I missing something obvious here?

Sub-question that I'd like to ask is, am I doing it correctly, architecture-wise? Perhaps there is a better tool for task that I have to accomplish...

Another approach I had in mind is something similar to handshake mechanism, where server maintains internal lookup table of connected client IDs (which can be even completely software-based and non-unique at any given moment), and tells client to come up with different ID during handshake, if duplicate ID is provided upon connection. That approach, unfortunately, doesn't play nicely with one of requirements to tie attributes to specific client during lifetime.