I'm writing an application that sends files over network, I want to develop a custom protocol to not limit myself in term on feature richness (http wouldn't be appropriate, the nearest thing is the bittorrent protocol maybe).

I've tried with twisted, I've built a good app but there's a bug that makes my GUI blocking, so I've to switch to another framework/strategy.

What do you suggest? Using raw sockets and using gtk mainloop (there are select-like functions in the toolkit) is too much difficult?

It's viable running two mainloops in different threads?

Asking for suggestions